WHITE PAPERS

In the rapidly evolving landscape of biotechnology, the transition from lab-scale discovery to industrial-scale production is often hindered by a single, persistent obstacle: protein expression yield. Conventional codon optimization tools, which have served the industry for decades, are increasingly proving insufficient for complex proteins or high-titer requirements.

In the push toward a more sustainable future, the ability to efficiently degrade bioplastics like polylactic acid (PLA) is essential. However, translating laboratory discoveries into industrial-scale solutions is often limited by the high volume of enzymes required for effective degradation. This white paper details how MNDL Bio’s proprietary AI-driven optimization enabled a two-fold increase in the expression of Cutinase Like Enzyme (CLE), overcoming significant biophysical hurdles that had previously restricted production.